Penza institute of Advanced MT,
Russia Ulyanovsk State University, Russia
Therapeutic correction testosterone deficiency in hypertensive men with erectile dysfunction and depression
Objective: The aim of this study was to evaluate of efficacy of comprehensive therapeutic correction testosterone deficiency in hypertensive patients with erectile dysfunction ( ED) and depression.
Methods : Seventy hve men (mean age was 50.2 ± 8.1 years) with arterial hypertension (1-111 stage) with ED and depression were studied. Erectile function was assessed by Interactional Index of Erectile Function — 5 questionnaire Men`s Sexual Formula (MSF); depression — by Hospital Anxiety and Depression Scale (HADS). Total testosterone (TT), dehydro-epiandrosterone sulfate (DHEAS), prolactin were measured in moming blood samples. For combination therapy natural origin medicine «Eromax» which includes such active ingredients as drone brood, bee pollen, and L-arginine was used.
Results: Out of total 75 men 65.3 % (49) by the 10th day of treatment noted subjective improvement in mood. increase of confidence in their sexual abilities, reduction of tension in marital relationships. The study of efficacy of the therapy in view of clinical and dynamic changes in hormonal status showed reliable increase in the TT level 9from 11,8± 4,4 to 17,1± 5,7 nM/l,P ˂ 0.02). There was also a tendency to increase of DHEAS (from 1,2 ± 0,3 to 1,6 ± 0,7 mcg/ml, P ˂ 0,05). During follow-up visit (28 th day of treatment) indicators IIEF rose from 15,8 ± 3,4 to 19,8 ± 3,7 (P ˂ 0/05). Against the carried out therapy the grade point average of MSF increased from 17,7± 2,5 to 23,8± 2,9 ( P ˂ 0,02). According to the HADS tested patients showed significant reduction in levels of anxiety and depression ( P ˂ 0,02).
Conclusion: The combined treatment with natural origin medicine «Eromax» significantly improves testosterone status, symptoms ED and depression in hypertensive men.
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